Northside Health Library Hemolytic anemia caused by chemicals and toxins
Hemolytic anemia caused by chemicals and toxins is a lack of red blood cells that occurs when red blood cells are excessively damaged by certain chemicals or toxins.
Anemia - hemolytic - caused by chemicals or toxins
Possible substances that can cause hemolytic anemia include:
Anti-malaria drugs (quinine compounds)
Intravenous water infusion (not half-normal saline or normal saline)
Metals (chromium/chromates, platinum salts, nickel compounds, copper, lead, cis-platinum)
Rho immune globulin (WinRho)
Snake bites (some snake venom contains hemolytic toxins)
This list is not all-inclusive.
Schwartz RS. Autoimmune and intravascular hemolytic anemias. In: Goldman L, Ausiello D, eds.
Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 163.
Schrier SL, Price EA. Extrinsic nonimmune hemolytic anemias. In: Hoffman R, Benz EJ, Shattil SS, et al., eds.
Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 48.
Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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