Hand-foot-and-mouth disease is a viral infection caused by Coxsackievirus that usually begins in the throat. Symptoms include; fever, sore throat, ulcers in the throat, headache, and a rash with blisters on the palms of the hands and soles of the feet.
Linda J. Vorvick, MD, Medical Director and Director of Didactic Curriculum, MEDEX Northwest Division of Physician Assistant Studies, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M. Health Solutions, Ebix, Inc.